Michele Boiani

Michele Boiani is a Research Professor and project leader at the Max Planck Institute for Molecular Biomedicine, where he heads the Mouse Embryology Laboratory within the Department of Cell and Developmental Biology. His research is funded by the Deutsche Forschungsgemeinschaft (DFG).

His work investigates fundamental mechanisms in developmental biology, focusing on:

• Totipotency apportionment in early mouse embryos
• Proteome dynamics and targeted protein degradation in oocytes
• Molecular bases of asymmetric mRNA distribution influencing embryonic development

Boiani's publications emphasize molecular and genomic analysis of preimplantation mouse embryos, utilizing techniques like multi-omics profiling and targeted proteolysis to study gene expression, protein function, and cellular totipotency.

He actively mentors PhD students, including Ellen Casser (2016–2019) and Steffen Israel (2017–2020), whose research on totipotency mechanisms and proteomics contributed significantly to the lab's output. The laboratory employs computational and experimental approaches to study embryogenesis, with ongoing investigations into COP9 signalosome complex functions.