معرفی
Michel Jadot is a researcher at the University of Namur, focusing on lysosomal biology, apoptosis, and inter-organelle communication. His work explores mechanisms of programmed cell death, lysosomal membrane protein functions, and interactions between mitochondria and lysosomes, with applications in cancer biology and metabolic disorders.
- Education: Doctor of Science (1986), University of Namur
Research Interests
His research spans Lysosomal Biology, Apoptosis, Signal Transduction, and Proteomics. Key areas include:
- Role of lysosomes in cell death regulation
- IGF1R/IGFII signaling in apoptosis resistance
- Mechanisms of lysosomal enzyme trafficking
- Mitochondria-lysosome communication
- Proteomic analysis of lysosomal membrane proteins
- Sterol metabolism and inter-organ communication
Collaborations and Publications
Recent work includes studies on:
- IGF1R-mediated apoptosis resistance in cancer cells
- SLC35F transporter localization in lysosomes
- Brucella abortus pathogenesis via mitophagy
- Lysosomal enzyme targeting in metabolic diseases
Supervised Work
He has supervised researchers including Aynaci, Toussaint, Gilis, Albert, Gaussin, and Boonen. His projects often involve multidisciplinary approaches linking molecular biology, proteomics, and cell signaling.
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