Michal Zigo

Michal Zigo is an Assistant Research Professor at the Division of Animal Sciences, University of Missouri. With expertise in reproductive biology, biochemistry, and swine reproduction, his work focuses on sperm physiology, particularly post-testicular sperm maturation and the role of the ubiquitin-proteasome system (UPS) in regulating sperm capacitation.

• B.S. in Biochemistry (2007), Charles University, Prague
• M.S. in Biochemistry (2009), Charles University, Prague
• Ph.D. in Biochemistry/Reproductive Biology (2014), Charles University, Prague
• Postdoctoral Fellow (2014-2019), University of Missouri
• Research Scientist (2020-present), University of Missouri

Zigo’s research investigates UPS-regulated proteomic remodeling during sperm capacitation, zinc ion flux as a fertility regulator, and neurodegenerative disease pathways in reproductive processes. He developed a zinc-based sperm fertility test and patented capacitation management media.

His publications span topics like sperm proteostasis, biomarker development, and proteasomal inhibition effects on motility. Awards include multiple Larry Ewing and MU Postdoctoral Association Travel Awards, USDA-NIFA-AFRI Merit Award, and international travel stipends.

• University of Missouri MU Postdoctoral Association Travel Award (2019)
• Larry Ewing Memorial Trainee Travel Award (2018, 2017, 2016)
• USDA-NIFA-AFRI Merit Award (2017)
• International travel stipends (2015, 2010)

Zigo is part of the Sutovsky Lab at the University of Missouri, where he advances capacitation management protocols for livestock improvement and explores cross-disciplinary links between reproductive biology and neurodegenerative disease mechanisms.