Michael J. Ryan

Michael J. Ryan, Ph.D., serves as Professor in the Department of Pharmacology, Physiology and Neuroscience at the University of South Carolina School of Medicine Columbia and holds the administrative role of Associate Chief of Staff for Research at the Columbia VA Health Care System.

His academic credentials include:

• Postdoctoral Fellowship: University of Iowa
• Ph.D. in Physiology & Biophysics: State University of New York College at Buffalo
• B.S. in Biological Sciences: State University of New York College at Cortland

Dr. Ryan's research program investigates chronic inflammation and immune dysfunction as drivers of hypertension, cardiovascular disease, and renal pathology. His laboratory employs autoimmune disorders—particularly systemic lupus erythematosus (SLE)—as models to dissect mechanistic links between autoantibodies and end-organ damage. Current NIH-funded work examines how autoantibodies target renal and vascular tissues to initiate hypertensive pathways, with implications for novel therapeutic interventions in both autoimmune patients and primary hypertension populations.

No scientific awards were referenced in the source documentation.

His laboratory operations are supported by active grant mechanisms focusing on autoimmune contributions to hypertension pathogenesis. While specific advisees aren't enumerated, his research program involves mentoring trainees in immunology and cardiovascular physiology methodologies. The laboratory is physically situated within the Shirley L. Buchanan Center (Building 9, Room 117c) at the Columbia VA campus, facilitating translational research through VA-university collaborations.