Michael B Gorin

Michael B. Gorin, M.D., Ph.D., is a Professor of Ophthalmology and Human Genetics at the University of California Los Angeles (UCLA) School of Medicine. He holds the Harold and Pauline Price Chair in Ophthalmology and has established himself as a leading researcher in ophthalmic genetics with contributions spanning molecular genetics, systems biology, and translational research in retinal diseases.

Dr. Gorin's research focuses on the genetic basis of age-related macular degeneration, inherited retinal diseases, and glaucoma. His laboratory employs a multidisciplinary approach combining human genetics, molecular biology, and advanced imaging techniques to investigate disease mechanisms and develop improved diagnostic methods. He has made significant contributions to identifying disease-causing genes, characterizing genotype-phenotype correlations, and developing novel approaches for variant interpretation in inherited retinal conditions.

Analysis of Dr. Gorin's recent publications reveals a strong emphasis on rare genetic variants associated with retinal diseases, particularly central serous chorioretinopathy, glaucoma, and Stargardt disease. His work often involves large-scale genomic studies and international collaborations aimed at understanding disease mechanisms at the molecular level and translating findings into clinical applications.

Dr. Gorin has received continuous research funding from the National Institutes of Health, including multiple R01 grants focused on the molecular genetics of X-linked cone-rod dystrophy, age-related maculopathy, and inherited retinal diseases. His laboratory has developed innovative approaches using patient-derived retinal pigment epithelial cells to assess variant pathogenicity and disease mechanisms.

His contributions extend to clinical practice through consensus guidelines for ocular surveillance in von Hippel-Lindau disease and efforts to improve diagnostic strategies for inherited retinal conditions. Dr. Gorin's work continues to bridge basic science discoveries with clinical applications, advancing our understanding and management of genetic eye diseases.