Mechta-Grigoriou Fatima

Fatima Mechta-Grigoriou is a Research Director (DR1) at Inserm and Group Leader of the 'Stress and Cancer' laboratory at Institut Curie, Paris. She leads research focused on tumor biology, oxidative stress, and pediatric oncology. Her academic journey includes a PhD from the Institut Pasteur and postdoctoral research at the ENS. She has held senior research roles since 2000, contributing to over 26 publications cited 2,496 times.

Education:

• DEA and PhD (1989-1994), Institut Pasteur, Paris
• Postdoctoral Fellow (1995-1999), ENS, Paris

Research Interests: Her work explores oxidative stress mechanisms in tumorigenesis, chemosensitivity, and tumor microenvironment interactions. She investigates stromal fibroblasts in breast and ovarian cancers and aging-related cancer vulnerabilities. Recently, she contributes to pediatric cancer research via the CONCERT unit, targeting solid tumors like medulloblastomas and neuroblastomas.

Awards:

• Chevalier of National Order of Merit (2013)
• Simone & Cino del Duca Prize (2006)
• Olga Sain Prize (2006)

Advising & Grants: Supervised 5 PhD students, 8 masters students, and 4 postdocs. Leads the Incentive Cooperative Program (PIC) on tumor stroma and co-organizes the European 'Breast Cancer Course.'

Labs/Teams: Heads the 'Stress and Cancer' lab within Inserm U830 and collaborates in the CONCERT unit (U1330), focusing on pediatric tumor mechanisms and immunotherapy.