Franck Bourdeaut

Franck Bourdeaut serves as Professor and Hospital Physician at Institut Curie, Paris, holding dual leadership roles as Deputy Director of the Children’s Oncology Research Unit (CONCERT, U1330) and Cancer, Hétérogénéité, Instabilité et Plasticité (CHIP, U830) research units. He leads the SMARCB1-deficient cancers team within the Translational Research Department, specializing in pediatric neuro-oncology for childhood cancers.

Education:

• Medical studies in Nantes
• Residency in Ile de France region
• Pediatrics degree (2004)
• Master’s/PhD under Dr. Olivier Delattre
• Chief resident in pediatrics (2006-2008)
• Dana-Farber Cancer Institute fellowship (Harvard Medical School)

His research pioneers understanding of SMARCB1-deficient cancers through genetic, transcriptomic, and epigenetic analyses of rhabdoid tumors and medulloblastoma. The team develops mouse models targeting embryonic progenitors to study tumor origins while investigating epigenetic vulnerabilities and tumor-immune interactions for novel therapies against these aggressive pediatric cancers.

Awards:

• Innovation Award in pediatric oncology (St Baldrick Foundation/SIOP, 2017) for rhabdoid tumor research

Accredited to supervise research since 2015, Bourdeaut mentors trainees within the Translational Research Department while securing funding for rare cancer studies. His team maintains close collaboration with Institut Curie’s pediatric department to accelerate clinical translation, utilizing advanced genomic platforms and preclinical models to overcome treatment resistance in SMARCB1-deficient malignancies.