Uwe Kordes

Uwe Kordes is a Clinical Professor and Senior Physician specializing in Pediatric Hematology and Oncology at the University Medical Center Hamburg-Eppendorf (UKE), affiliated with the University of Hamburg Faculty of Medicine. He leads the Department of Pediatric Hematology and Oncology within the Center for Obstetrics and Pediatrics. His work focuses on neuro-oncological challenges, particularly choroid plexus tumors, rhabdoid tumors, and genetic syndromes such as Li-Fraumeni syndrome. He collaborates on multi-institutional trials and registries, including the CPT-SIOP registry for choroid plexus tumors.

Research interests include molecular profiling of pediatric brain tumors, therapeutic strategies for high-risk malignancies, and genetic predisposition to cancer. Kordes has contributed to over 80 peer-reviewed publications, emphasizing translational research and clinical outcomes. Key collaborations involve institutions like the European Rhabdoid Registry (EU-RHAB) and the Mildred Scheel Foundation.

Notable contributions include defining molecular subgroups in atypical teratoid/rhabdoid tumors (ATRT) and advancing targeted therapies for BRAF-mutant gliomas. He also investigates the role of germline mutations in cancer predisposition syndromes.