معرفی
Irwin McLean is a distinguished academic with roles including Schwartz Professor of Genetic Medicine at the PC Project (Salt Lake City, Utah, USA) and Emeritus Professor of Genetic Medicine at the University of Dundee's School of Life Sciences. He holds Honorary Consultant Clinical Scientist positions in Dermatology and Human Genetics with NHS Tayside. His career spans over three decades, including leadership roles at the University of Dundee and Jefferson Medical College.
Education: BSc (Hons) Microbiology (1985), PhD Human Genetics (1988), DSc Human Genetics (keratinizing disorders) – all from The Queen's University of Belfast.
Research Interests: McLean's work focuses on human molecular genetics, particularly keratin-related disorders and filaggrin's role in skin barrier function. His breakthrough discovery of filaggrin's link to atopic dermatitis has revolutionized understanding of allergic disease mechanisms. Current efforts emphasize translational therapies for epidermal and corneal disorders.
Awards:
- 2020: Fellow of the Royal Society of Arts (FRSA)
- 2014: Elected Fellow of the Royal Society (FRS)
- 2015: Buchanan Medal (Royal Society)
- 2009: American Skin Association Achievement Award
Advising & Grants: Leads UK diagnostic services for keratinizing disorders and collaborates closely with patient organizations like DEBRA. His research has attracted multimillion-pound funding for siRNA and small molecule therapies.
Labs & Teams: Director of the Centre for Dermatology and Genetic Medicine at Dundee, integrating clinical diagnostics, genetic counseling, and translational research programs.
