Alan David Irvine

Alan David Irvine is a Professor in Dermatology at Trinity College Dublin, with clinical affiliations at Children's Health Ireland at Crumlin and St. James's Hospital in Dublin. He trained in Dermatology and Genetics in Belfast, Great Ormond Street Hospital, and Northwestern University as a Fulbright Scholar.

His research focuses on improving lives for individuals with inflammatory and genetic skin disorders through studying skin barrier function, host-microbiome interactions, and drug development. He co-discovered filaggrin variants as a key predisposing factor for atopic dermatitis and asthma, a paradigm-shifting finding in allergy pathogenesis.

• First to link filaggrin mutations to atopic diseases (Nature Genetics 2006)
• Identified skin microbiome's protective role against eczema (JACI 2017)
• Demonstrated dose-dependent effects of filaggrin CNVs (JID 2012)

His awards include the Paul Gerson Unna Prize (German Dermatological Society), Marion Sulzberger Memorial Award (AAD), and Research Project of the Year in Times Higher Education Awards. He is a Fellow of the Royal Society of Edinburgh and member of the Royal Irish Academy.