Mazyar Shadman

Dr. Mazyar Shadman is a Professor in the Clinical Research Division at Fred Hutch Cancer Center and Professor in the Division of Hematology and Oncology at the University of Washington School of Medicine. He serves as Medical Director of Cellular Immunotherapy and the Bezos Family Immunotherapy Clinic at Fred Hutch, where he holds the Innovators Network Endowed Chair. His clinical practice focuses on adult blood and marrow transplantation for hematologic malignancies.

Education:

• M.D. from Tehran University of Medical Sciences (2004)
• M.P.H. in Cancer Epidemiology from University of Washington (2008)
• Internal Medicine Residency at Cleveland Clinic (2009-2011)
• Hematology-Oncology Fellowship at University of Washington/Fred Hutch (2011-2014)

Research Focus: Dr. Shadman specializes in therapeutic clinical trials for lymphoid malignancies, particularly chronic lymphocytic leukemia (CLL) and small lymphocytic lymphoma (SLL). His work integrates novel therapeutic agents, CAR T-cell immunotherapy, and stem cell transplantation, with parallel research in clinical outcomes and epidemiology of hematologic malignancies. He aims to identify optimal treatment sequences for high-risk lymphoma and CLL patients.

Leadership & Recognition:

• Medical Director of Bezos Family Immunotherapy Clinic
• Member of Immunotherapy Integrated Research Center
• Recipient of Innovators Network Endowed Chair (2023)