Stephen Douglas Smith

Stephen Douglas Smith, MD, serves as an Associate Professor in the Division of Hematology and Oncology at the University of Washington School of Medicine and in the Clinical Research Division at Fred Hutch Cancer Center. Board-certified in Hematology, Medical Oncology, and Internal Medicine, he specializes in treating lymphoma, chronic lymphocytic leukemia (CLL/SLL), and other blood disorders with a focus on immunotherapy and targeted therapies.

Education:

• MD, Keck School of Medicine, University of Southern California (2002)
• BS, Biological Sciences, Stanford University (1997)
• Residency and Internship, Internal Medicine, Los Angeles County/USC Medical Center
• Fellowship, Hematology and Oncology, Cleveland Clinic Foundation Program (2008)

Research Interests: Dr. Smith's research centers on advancing hematologic malignancy treatments through novel targeted therapies and immunotherapies. He investigates kinase inhibitors, hematologic stem cell transplantation, and lymphoma databases to develop personalized prognostic models, aiming to improve patient outcomes via cutting-edge clinical trials.

Grants and Clinical Trials: He leads an NCCN grant (2014-2016) for Waldenström’s Macroglobulinemia research and actively contributes to multiple clinical trials evaluating new lymphoma treatments, ensuring patient access to innovative therapies.

Care Team: At Fred Hutch, Dr. Smith collaborates with a multidisciplinary team including nurses, dietitians, social workers, and psychiatrists to deliver comprehensive cancer and blood disorder care across Pacific Northwest treatment sites.