Matthieu Defrance

Matthieu Defrance is an Associate Professor in the Computer Science Department at Université Libre de Bruxelles (ULB), Belgium, a position he has held since October 2016. Prior to this, he worked as a PostDoc at ULB's Laboratory of Cancer Epigenetics from May 2010 to September 2016.

Dr. Defrance's research bridges computer science with biological sciences, focusing on computational methods for analyzing complex biological data. His work spans epigenetics, genomics, and algorithm development for biological applications.

His primary research interests include:

• Gene Regulation and Chromatin Biology
• Epigenetics and Epigenomics
• DNA Methylation analysis
• Computational Statistics for biological data
• Algorithm Development for genomic applications
• Next Generation Sequencing data analysis

Dr. Defrance's publication record demonstrates a strong interdisciplinary approach, with recent work focusing on improving DNA methylation analysis techniques, developing novel bioinformatics tools like RedRibbon for gene expression signature comparison, and applying these methods to understand diseases like diabetes and cancer.

His research shows consistent innovation in computational biology, with publications spanning from method development to biological applications across diverse fields including diabetes genetics, cancer epigenetics, and evolutionary adaptations in desert ants.

With 61 publications and nearly 5,000 citations, Dr. Defrance has established himself as a significant contributor to computational biology and epigenetics research.