Matthias Kretzler

Matthias Kretzler, MD is the Warner-Lambert/Parke-Davis Professor of Medicine and a Research Professor at the University of Michigan Medical School, Department of Computational Medicine and Bioinformatics. His work focuses on the molecular pathophysiology of glomerular diseases through integrative systems biology approaches.

• Education:
  • Baccalaureate from St. Paulusheim (1985)
  • MD from University of Heidelberg (1992)
  • PhD from University of Heidelberg (1993)
• Research Interests:
  • Integrative systems biology of renal disease with emphasis on glomerular disorders
  • Molecular diagnostics and target identification in kidney disease
  • Computational modeling of disease mechanisms
• Center Memberships:
  • Biosciences Initiative
  • MExperts-Center for Global Health Equity
  • Global REACH
  • Precision Health Initiative
  • MM-PKUHSC Joint Institute
  • Center for Computational Medicine and Bioinformatics
  • Caswell Diabetes Institute
• Recent Research Trends:
  • Developing computational frameworks for integrative disease mapping
  • Investigating mitochondrial metabolism in renal epithelial stress adaptation
  • Linking environmental factors (e.g., air pollutants) to glomerular disease progression
  • Exploring immunophenotyping for lupus nephritis stratification
  • Elucidating genome maintenance in podocyte damage mechanisms