James McCaffrey

Dr. James McCaffrey is a Clinical Senior Research Associate at the Department of Medicine, University of Cambridge, and a Fellow in Medical Sciences at Downing College. He holds qualifications including a PhD, MRCPCH, FRCPath, and FHEA.

• BA (Oxon)
• BM BCh (Oxon)
• PhD
• MRCPCH
• FRCPath
• FHEA

McCaffrey's research applies advanced molecular techniques to human kidney tissue, focusing on pathophysiological mechanisms in kidney transplantation and inflammatory renal diseases like lupus nephritis and ANCA-associated vasculitis. He leads the Molecular Diagnosis in Renal Pathology (MDiRP) study and manages two Human Tissue Authority-licensed Research Tissue Banks on the Cambridge Biomedical Campus.

His scientific work spans molecular diagnostics, immune cell dynamics in kidney disease, biomarker development for acute kidney injury, and nanomedicine applications in renal physiology. Publications highlight collaborations in pediatric nephrology, epigenetics, and transplantation outcomes.

McCaffrey has contributed to clinical guidelines and research on corticosteroid-minimised immunosuppressive regimens, viral infections in pediatric transplants, and glomerular disease management. His work bridges laboratory research with clinical applications in renal medicine.