Matthew Smith

Matthew Smith is a Professor in Biomedical Engineering and Neuroscience Institute with a focus on computational and systems neuroscience. As Co-Director of the Center for the Neural Basis of Cognition, his research explores neural circuits, motor control, and spatial cognition. His work bridges experimental and computational methods, including studies on neural plasticity, electrophysiological recordings, and non-invasive neurostimulation techniques. Key contributions include advancing methods for estimating intracranial pressure and optimizing brain stimulation protocols. His interdisciplinary approach integrates machine learning, statistical analysis, and neuroimaging to understand complex brain functions.

Research interests span neural coding mechanisms, visual perception dynamics, and the interplay between arousal systems and motor planning. Notable projects include investigations into V4 neuronal activity modulation by recent experience and the development of compact deep neural network models for visual cortex analysis. Smith’s lab employs advanced signal processing tools, such as SLEX analysis and latent dynamic factor modeling, to decode high-dimensional neural data.

His recent publications highlight breakthroughs in understanding working memory robustness, transcranial ultrasound modulation specificity, and the spatial organization of prefrontal cortical networks. While no formal awards are listed, his extensive grant-funded research includes collaborations on cerebral autoregulation studies and neurovascular impedance modeling. Advising activities focus on training interdisciplinary PhD candidates in systems neuroscience and neural computation.