معرفی
Dr. Matthew Rose-Zerilli is a Lecturer in Integrative Cancer Biology at the University of Southampton, School of Cancer Sciences. His research focuses on stopping oesophageal cancer development through immunoprevention strategies, leveraging innate immune cell activities and tumour microenvironment dynamics. He collaborates across disciplines to develop novel therapies, particularly targeting cancer-associated fibroblasts and immunomodulatory pathways.
Education: BSc (Hons) in Biochemistry from the University of Portsmouth (2002), PhD in Genetics from the University of Southampton. Career highlights include a John Goldman Fellowship (2016) and a Faculty of Medicine Career Track Fellowship (2014).
Research interests span cancer prevention, innate immunity, tumour microenvironment, and genetic evolution in cancers like oesophageal adenocarcinoma. Recent work includes studies on phosphodiesterase inhibitors enhancing chemotherapy efficacy, fibroblast subpopulation roles in lung cancer prognosis, and Fcγ receptor impacts on antibody therapies.
Teaching roles include leading the Quantitative Cell Biology module and co-leading Genomic Technologies and Basic Informatics. He mentors PhD students in cancer sciences and related fields.
- Grants: CRUK Biology to Prevention Award, Breast Cancer Now, Sarcoma UK.
- Labs/Teams: Leads a research group within the School of Cancer Sciences, collaborating with the Centre for Cancer Immunology and Institute for Life Sciences.
