معرفی
Matthew Kirchner, PhD is an Assistant Professor in the Department of Medical Physiology at Texas A&M University's School of Medicine. His research focuses on neurophysiological mechanisms underlying hypothalamic neuropeptide signaling, particularly oxytocin and vasopressin systems, with emphasis on calcium channel dynamics, somatodendritic release mechanisms, and their roles in cardiovascular regulation and metabolic disorders. He holds a BA in Neuroscience and Philosophy from College of Wooster (2013), PhD in Neuroscience from University of Tennessee Health Science Center (2018), and postdoctoral training in Neurophysiology at Georgia State University (2018-2025).
Research interests include: 1) Calcium-dependent potassium channel regulation of neuronal excitability, 2) Neuroendocrine adaptations in heart failure models, 3) Microglial-neuronal interactions in chronic disease states. His lab employs patch-clamp electrophysiology, live calcium imaging, and acute brain slice preparations to study these systems.
Recent work highlights impaired oxytocin signaling in heart failure rats, mitochondrial-calcium interactions in vasopressin neurons, and novel blood pressure regulation pathways via angiotensin receptors in the amygdala. He collaborates extensively with neuroendocrinology groups studying stress axes and metabolic control.
