Maryellen L. Giger

Maryellen L. Giger, Ph.D. is the A.N. Pritzker Distinguished Service Professor of Radiology, Committee on Medical Physics, and the College at the University of Chicago. She serves as Vice-Chair of Radiology (Basic Science Research) and was the immediate past Director of the CAMPEP-accredited Graduate Programs in Medical Physics/Chair of the Committee on Medical Physics. Her career spans over 30 years of pioneering research in computer-aided diagnosis, machine learning, and deep learning applications in medical imaging.

Dr. Giger's research focuses on computational image-based analyses for cancer risk assessment, diagnosis, prognosis, and response to therapy, particularly in breast cancer, lung cancer, prostate cancer, lupus, bone diseases, and more recently, COVID-19. Her work has evolved from developing computer-aided diagnosis systems to utilizing 'virtual biopsies' in imaging genomics association studies for discovery. She has made significant contributions to quantitative imaging, radiomics, and AI applications in medical imaging, with emphasis on translating research into clinical practice.

Her publication record shows a clear trajectory from foundational work in computer vision for medical imaging to cutting-edge AI and deep learning applications. The recent publications demonstrate her leadership in large-scale collaborative efforts like the Medical Imaging and Data Resource Center (MIDRC), focus on health equity through AI analysis, and expansion into diverse applications including gynecological imaging, lung cancer screening, and trauma assessment. Her work consistently bridges technical innovation with clinical relevance.

Dr. Giger has received numerous prestigious honors including membership in the National Academy of Engineering, the William D. Coolidge Gold Medal (the highest award from AAPM), and being named one of the 50 most impactful medical physicists in the last 50 years. She is a Fellow of multiple professional societies including AAPM, AIMBE, SPIE, SBMR, and IEEE. Her 2019 TIME magazine recognition for QuantX, the first FDA-cleared machine-learning-driven system for cancer diagnosis, highlights her translational impact.

As an educator and mentor, Dr. Giger has guided over 100 graduate students, residents, and medical students throughout her career. She has secured substantial research funding including NIH R01 grants and serves as contact PI for the NIH NIBIB-funded & ARPA-H-funded Medical Imaging and Data Resource Center (MIDRC). Her leadership extends to former presidencies of the American Association of Physicists in Medicine and SPIE, and she was the inaugural Editor-in-Chief of the SPIE Journal of Medical Imaging.

Dr. Giger co-founded Quantitative Insights, Inc. through the University of Chicago's New Venture Challenge, which developed QuantX - the first FDA-cleared AI system for cancer diagnosis. She leads the Medical Imaging and Data Resource Center (MIDRC), a critical resource for AI development in medical imaging that received the 2023 DataWorks Prize. Her research laboratory bridges engineering, physics, and clinical medicine to develop and validate quantitative imaging biomarkers and AI tools for precision medicine.