Martina Leopizzi

Dr. Martina Leopizzi is a Researcher at the Department of Medical-Surgical Sciences and Biotechnologies at Sapienza University of Rome, where she conducts significant research in bone diseases and cancer biology. Her institutional affiliation places her within the Faculty of Medicine at one of Italy's most prestigious academic institutions.

Dr. Leopizzi's primary research focus centers on osteosarcoma, with particular emphasis on Phosphoinositide-specific Phospholipase C (PI-PLC) enzymes and their role in cancer cell migration, invasion, and metastasis. Her work extends to studying cellular signaling pathways in bone cancer, including research on Ezrin, Rho and Ras GTPase proteins. More recently, she has expanded her investigations to include osteosarcoma-derived extracellular vesicles and their molecular composition.

Analysis of Dr. Leopizzi's publication record from 2022-2025 reveals a significant evolution in her research scope. While maintaining her core focus on bone cancer and cell signaling, she has progressively expanded into immunology, virology, and cardiovascular research. Her recent work demonstrates particular interest in tumor immunology, with multiple publications examining immune checkpoint proteins like PD-L1 and their role in various cancers. The interdisciplinary nature of her research is evident in publications spanning oncology, immunology, rheumatology, and hematology.

Dr. Leopizzi's research methodology appears to emphasize molecular and cellular approaches, with frequent use of immunohistochemistry, cell line studies, and analysis of protein expression patterns. Her work often bridges basic science with clinical applications, particularly in cancer diagnostics and treatment.