معرفی
Kay Oliver Schink is an Associate Professor at the University of Oslo, leading the Membrane Trafficking Group at the Department of Molecular Cell Biology, Institute for Cancer Research. His research examines membrane dynamics, phosphoinositide signaling, and vesicle trafficking mechanisms, particularly in cancer contexts like macropinocytosis-mediated nutrient scavenging.
Education:
- Diploma in Biological Sciences from Philipps-University Marburg, specializing in genetics, virology and parasitology
- PhD in Biological Sciences from Philipps-University Marburg, focusing on Rho GTPase regulation by phosphoinositides
Research Focus: Dr. Schink investigates how phosphoinositides and Rab GTPases control vesicle identity, macropinosome formation, and cancer metabolism. His lab employs advanced microscopy (light sheet, super-resolution) and develops optogenetic tools to study membrane remodeling. Key projects include KRAS-driven cancer metabolism and autophagy mechanisms.
Publication Trends: Recent articles (2019-2025) predominantly explore membrane trafficking regulation, autophagy mechanisms, and cancer cell adaptations. Over 60% focus on phosphoinositide signaling, while 30% examine vesicle dynamics in disease contexts. Methodological papers detail advanced imaging techniques.
Funding & Collaborations: Supported by the Norwegian Research Council, Cancer Society, and Helse Sør-Øst. Key collaborations include Coen Campsteijn (UiO), Harald Stenmark (Oslo University Hospital), Frauke Ackermann (Charité Berlin; synaptic trafficking), and Johannes Freitag (University of Marburg; peroxisomes). Affiliated with the CanCell Center of Excellence.
Laboratory: The Membrane Trafficking Group specializes in live-cell imaging, phosphoinositide tracking, and developing synthetic biology tools for manipulating lipid/protein interactions. The team employs deep learning for image analysis of vesicle dynamics.
