Markus Grompe

Markus Grompe is the Ray Hickey Professor and Director of the Papé Family Pediatric Research Institute at Oregon Health & Science University. His research focuses on advancing gene and cell transplantation therapies for inherited diseases, particularly through the study of hepatic stem cells and therapeutic liver repopulation. He has pioneered murine models supporting human stem cell expansion and developed humanized mice as platforms for novel therapeutics, including AAV vectors and small molecules.

Dr. Grompe has published over 200 peer-reviewed articles and holds multiple patents. His work spans disciplines such as

• Gene Therapy
• Stem Cell Biology
• Hepatology
• Molecular Genetics

with a strong emphasis on translational applications for liver diseases and Fanconi anemia.

Recent publications highlight trends in

• AAV vector optimization
• CRISPR/Cas9 editing
• metabolic and hematologic disease models
• bioinformatic tools like RAAVioli

. His studies often bridge in vivo experimentation with clinical translation, prioritizing safety and efficacy in gene therapy.