Holger Willenbring

Holger Willenbring is a Professor in the Department of Surgery at the University of California, San Francisco (UCSF) School of Medicine. His research focuses on liver regeneration, hepatocyte biology, and stem cell-based therapies for liver diseases.

• Institution: University of California, San Francisco
• School: School of Medicine
• Department: Surgery

Dr. Willenbring's work spans several critical areas including:

• Liver regeneration mechanisms.
• Induced pluripotent stem cell (iPSC) applications in liver disease modeling.
• Adeno-associated virus (AAV) vector development for gene therapy.
• Cell transdifferentiation strategies for treating biliary and metabolic liver disorders.
• Microphysiological systems for studying liver-heart-adipose interactions.

His recent publications highlight advancements in liver gene therapy, iPSC-based models for diabetes and cancer, and AAV vector optimization. Key trends include:

• Development of microphysiological systems for drug testing.
• Investigation of hepatocyte proliferation and transdifferentiation.
• Applications of stem cell technology in regenerative medicine.