Aras Mattis

Aras Mattis, MD, PhD is an Associate Professor at the University of California, San Francisco (UCSF) School of Medicine, affiliated with the Department of Pathology. His research bridges clinical pathology with cutting-edge stem cell and metabolic liver disease studies.

• Education: BA in Molecular and Cell Biology - Genetics (UC Berkeley), PhD in Biochemistry (University of Illinois), MD in Medicine (University of Illinois)
• Current NIH-funded projects: Modeling NAFLD phenotypes (R01DK132129), iPSC platforms for liver research (RC2DK136052), genetic regulation of NAFLD (R01DK130391), and prior K08DK098270 on miR-29a

Research focuses on nonalcoholic fatty liver disease (NAFLD), induced pluripotent stem cells (iPSCs), and hepatocyte biology, with significant work on genetic regulation and metabolic liver disease. His recent publications emphasize stem cell-derived liver models, microRNA mechanisms, and gene therapy for metabolic disorders.

Key article trends include:

• NAFLD modeling (11% of recent work)
• iPSC applications (17%)
• Liver fibrosis (23%)
• DNA flow cytometry (29%)
• MicroRNA regulation (14%)
• Gene therapy (6%)

Collaborations span multiple institutions with notable co-authors including Holger Willenbring, Jacquelyn Maher, and Marisa Medina. His work appears in journals like Nature Biotechnology, Gastroenterology, and Hepatology, with significant citations in translational medicine and cell biology.