Mark Looney

Mark Looney is a practicing pulmonologist and intensivist at the University of California San Francisco, conducting groundbreaking research in acute lung injury. His work integrates clinical practice with experimental modeling to uncover pathogenic mechanisms and test novel therapeutics, particularly in transfusion-related injuries and viral pathogenesis.

Research Focus: His laboratory investigates

• Neutrophil extracellular traps (NETs) in SARS-CoV-2 infection
• Antibody-mediated lung injury mechanisms
• Hematopoietic progenitor cells in lung immunity
• Complement activation in lung pathology
• Role of NK cells in ischemia-reperfusion injury
• Platelet-megakaryocyte biology in lung homeostasis and injury

Scientific Awards:

• Will Rogers Fellowship Award (2002)
• GlaxoSmithKline Pulmonary Fellowship Award (2004)
• Carl Booberg Research Award (2009)
• Jean Julliard Prize (2013)
• Member, The American Society for Clinical Investigation

Grants:

• NIH R01AI160167 (2021-2026): SARS-CoV-2 and NETs
• NIH R01HL138673 (2019-2022): Antibody-mediated lung injury
• NIH R01AI125445 (2016-2021): Neutrophil response to pneumonia
• NIH R01HL107386 (2011-2021): Platelet biology in lung injury
• NIH R01HL130324 (2016-2020): Innate immunity in lung transplantation