معرفی
Amanda M Jamieson is the Esther Elizabeth Brintzenhoff Associate Professor of Molecular Microbiology and Immunology at Brown University's School of Public Health. She serves as Co-Director of the Pathobiology Graduate Program and Director of the NIH Postbaccalaureate Research Education Program (PREP). Her research focuses on host resilience mechanisms to pulmonary diseases through interdisciplinary collaborations with pulmonologists, surgeons, and neuroscientists.
Her primary research areas include:
- Host tolerance mechanisms during pulmonary infections
- Immune triage in response to competing inflammatory insults
- Lung microbiome interactions in cancer and immunity
- Neural-immune-vascular crosstalk in infection
- Coagulation pathologies in respiratory viruses
Analysis of her 15 most recent publications reveals a strong emphasis on viral-bacterial coinfections (particularly influenza/SARS-CoV-2 with bacterial pathogens), wound healing complications during pulmonary infections, and neural-immune interactions in inflammatory responses. Her work increasingly incorporates machine learning approaches for immune cell phenotyping and explores therapeutic interventions for coagulopathies.
Notable scientific awards include:
- 2022 Carleton College Distinguished Achievement Award
- 2021 Dean's Award for Excellence in Teaching
- 2018 Society for Leukocyte Biology Women and Diversity Paper Award
- 2014 Salomon Research Award
Jamieson directs multiple major research initiatives including an R01HL165259 grant investigating Caspase-8 in host tolerance during respiratory infections, an NHLBI R01 on lung microbiome influences, and a Rhode Island Foundation grant targeting Caspase-8 therapeutics. She has secured continuous funding since 2012 from NIH, DARPA, and private foundations totaling over $15 million.
Her laboratory develops innovative models for studying viral/bacterial pulmonary coinfections, tissue resilience during infection, and innate immune prioritization between lung infections and cutaneous wounds, with particular focus on macrophage responses and chemokine signaling pathways.
