معرفی
Mark Gomelsky is a Professor in the Department of Molecular Biology at the University of Wyoming. He earned his Ph.D. in Biological Sciences from the Institute for Genetics and Selection of Industrial Microorganisms in Moscow, Russia, and completed post-doctoral training at Institut Pasteur in Paris and the University of Texas Medical School in Houston. His research spans bacterial signal transduction, photoreception, and synthetic biology, with a focus on cyclic di-GMP (c-di-GMP) signaling, Listeria-plant biofilms, and engineered bacterial systems for medical applications.
- Education:
- Ph.D. in Biological Sciences (1991), Institute for Genetics and Selection of Industrial Microorganisms, Moscow, Russia
- Post-doctoral training, Institut Pasteur, Paris, France
- Post-doctoral training, University of Texas Medical School, Houston, USA
Dr. Gomelsky’s research has pioneered c-di-GMP signaling in bacteria, revealing its role in biofilm formation and virulence. His lab discovered novel photoreceptors and engineered near-infrared light-activated enzymes for optogenetic applications, including diabetes and neuronal regulation. Key projects include:
- Listeria-plant biofilms: Investigating exopolysaccharide synthesis and contamination prevention on fresh produce.
- Listerial bactodrones: Developing genetically modified Listeria strains for targeted cancer therapy via tumor microenvironment activation.
- Metabolic engineering: Manipulating Rhodobacter sphaeroides for hydrogen production and asymmetric bacterial cell division.
His publications emphasize bacterial signaling, biofilm dynamics, and optogenetic tools. Over 90 research papers reflect his expertise in molecular microbiology and synthetic biology. Awards include AAAS Fellowship (2016) and the Jack Kenney Award (2016). Lab members include postdocs, Ph.D. students, and research assistants, with collaborations across microbiology, synthetic biology, and medical applications.
