معرفی
Mark Estacion is a Research Scientist in the Department of Neurology at Yale University School of Medicine. His research focuses on neurophysiology, electrophysiology, and ion channel function, particularly sodium channels like Nav1.7 and their role in pain pathways and neurological disorders.
Dr. Estacion received his BS from Harvey Mudd College in 1982 and his PhD from the University of California, Irvine in 1989. His academic career includes research positions at MetroHealth Medical Center, University of California, Irvine, and University of Hawaii.
His research interests span Biophysics, Electrophysiology, Neurophysiology, Neurosciences, and Physiology, with a particular focus on voltage-gated sodium channels and their role in pain syndromes. His work combines molecular, cellular, and electrophysiological approaches to understand channel function and develop targeted therapies for pain conditions.
Dr. Estacion's recent publications demonstrate a strong focus on high-throughput electrophysiological techniques, sodium channel structure-function relationships, and the development of targeted therapies for pain conditions. His research spans basic science investigations of channel biophysics to clinical applications in pain management, reflecting a highly translational approach to neuroscience research.
- Extensive work on Nav1.7 sodium channel and its role in pain pathways
- Development of high-throughput electrophysiological screening methods
- Investigation of channel mutations in pain disorders like small fiber neuropathy and erythromelalgia
- Pharmacological targeting of sodium channels for pain management
Dr. Estacion collaborates extensively with researchers including Sulayman Dib-Hajj, Stephen Waxman, Peng Zhao, Betsy Schulman, Mohammad-Reza Ghovanloo, and Sidharth Tyagi, reflecting a highly collaborative research approach focused on understanding and treating neurological pain conditions.