Marion R. Curtis

Marion R. Curtis, Ph.D., is an Associate Professor of Immunology at Mayo Clinic in Phoenix, Arizona, where she conducts research within the Department of Research, focusing on Immunology and Cancer Biology. She leads the Immunometabolism and Cancer Immunology Laboratory, dedicated to improving outcomes in ovarian cancer through innovative immunological research.

Research Interests:
Dr. Curtis' research centers on understanding how the tumor microenvironment regulates immune cell metabolism and how this metabolic state influences cancer metastasis and response to immunotherapy. Her lab employs cutting-edge techniques such as metabolomics, proteomics, advanced cellular imaging, co-culture systems, and mouse models. A major focus is on identifying tumor-associated antigens via immunopeptidomics to develop personalized immunotherapies, including multiantigen dendritic cell vaccines for advanced-stage ovarian cancer.

Scientific Awards:

• Ann and Sol Schreiber Mentored Investigator Award, Ovarian Cancer Research Alliance (2017)
• Travel Award, Biological Sciences Division Postdoctoral Association Symposium, University of Chicago (2016)

Advising and Grants:
While specific students are not listed, Dr. Curtis leads a research team and is involved in training and mentorship opportunities, including postdoctoral fellowships and training grant programs at Mayo Clinic. Her research is supported by competitive grants, notably the Mentored Investigator Award from the Ovarian Cancer Research Alliance.

Labs and Teams:
Dr. Curtis directs the Immunometabolism and Cancer Immunology Laboratory at Mayo Clinic’s Scottsdale campus. Her interdisciplinary team integrates immunology, cancer biology, and metabolic research to translate findings into clinical applications for ovarian cancer patients.