Laura M. Rogers

Laura M. Rogers, Ph.D., is an Assistant Professor of Immunology at Mayo Clinic in Rochester, Minnesota, where she leads a research laboratory focused on cancer immunotherapy and immune cell dynamics in the tumor microenvironment. She is affiliated with the Department of Immunology and the David F. and Margaret T. Grohne Cancer Immunology and Immunotherapeutics Program under the Mayo Clinic Comprehensive Cancer Center.

Education:

• Ph.D. in Anatomy and Cell Biology, University of Iowa
• M.S. in Bioinformatics, University of Iowa
• B.S. in Microbiology (with honors), University of Iowa; Minor in Music

Dr. Rogers' research centers on understanding the genetic determinants of immune cell infiltration into tumors, particularly how T cell trafficking is regulated by surface protein expression, cellular metabolism, and viability. Her lab uses the Sleeping Beauty transposon system and bioinformatics to identify novel molecular regulators of immune infiltration and validate their function using in vivo and in vitro models. This work has significant implications for enhancing the efficacy of T cell-mediated immunotherapies like CAR-T and checkpoint blockade in patients with poorly infiltrated tumors.

Her research integrates forward genetic screens with large-scale genomic data to uncover functional contributors to immunotherapy response and resistance, aiming to develop better biomarkers and therapeutic strategies. Though specific publications are referenced, no article titles were listed in the source text.

Scientific Affiliations and Roles:

• Senior Associate Consultant I-Research, Department of Immunology, Mayo Clinic
• Faculty Member, Mayo Clinic Comprehensive Cancer Center
• Researcher, David F. and Margaret T. Grohne Cancer Immunology and Immunotherapeutics Program

Dr. Rogers is actively involved in mentoring and research training, with opportunities for postdoctoral fellowships and grant-supported positions in her lab. She contributes to institutional research infrastructure through involvement in core facilities, clinical trials, and multidisciplinary cancer research programs.

Laboratory and Research Environment:

Her laboratory is part of a robust immunology and cancer research ecosystem at Mayo Clinic, utilizing cutting-edge genetic, genomic, and preclinical modeling approaches. The lab collaborates within interdisciplinary teams focused on advancing cancer immunology and developing novel immunotherapeutic interventions.