Maria M. Aleman

Maria M. Aleman, PhD is an Assistant Professor in the Department of Pharmacology at the University of North Carolina at Chapel Hill School of Medicine. Her research focuses on understanding fundamental mechanisms of erythropoiesis, blood and vascular biology, and the intersection of RNA regulation with iron metabolism in non-malignant hematology.

Dr. Aleman's primary research interests center on erythropoiesis (red blood cell differentiation and maturation), investigating how hematopoietic stem cells differentiate through multiple stages until committing to the erythroid lineage. Her work particularly examines the family of dual functional proteins known as poly C binding proteins, which both regulate RNA processing and chaperone iron within cells. Using biochemical, cellular, and in vivo models, her laboratory explores the cross talk between iron trafficking and RNA regulation mediated by these proteins and how these activities are modulated by disease.

Analysis of Dr. Aleman's publication record reveals a strong focus on hemostasis, thrombosis, and coagulation disorders, with significant contributions to understanding venous thrombosis mechanisms, factor VIII therapies for hemophilia A, and the role of various proteins in blood clotting processes. Her work bridges basic science with clinical applications, particularly in non-malignant blood disorders.

Dr. Aleman maintains an active research laboratory (the Aleman Lab) at UNC Chapel Hill, where she investigates the basic mechanisms regulating erythropoiesis. Her work combines expertise in pharmacology, hematology, and molecular biology to address fundamental questions about blood cell formation and function. While specific grant information isn't detailed in the available materials, her consistent publication record across multiple high-impact journals suggests sustained research funding in her areas of expertise.