معرفی
Maria Allhorn is a Researcher at Lund University with active affiliations to the Lund University Cancer Centre (LUCC), StemTherapy: National Initiative on Stem Cells for Regenerative Therapy, and Transfusion Medicine. Her work contributes to UN Sustainable Development Goals in health and well-being, focusing on infectious medicine and cancer research through biochemical and medical investigations of oxidative stress mechanisms.
Her research centers on Alpha-1-Microglobulin (A1M), a lipocalin protein with radical scavenging properties. Key contributions include molecular characterization of A1M's binding to heparin/heparan sulfate, protective roles against hemolysis and oxidative stress, and therapeutic applications using recombinant variants. Studies with A1M knockout mice revealed macrocytic anemia phenotypes, while collaborative work explores bacterial effector molecules like RoxP from Propionibacterium acnes for inflammation mitigation.
Analysis of her 2019-2025 publications shows cohesive focus on A1M's therapeutic potential across diverse pathologies. Research consistently bridges fundamental biochemistry with clinical translation in transfusion medicine, nephrology, and oncology, emphasizing molecular mechanisms of oxidative damage protection and novel treatment development for conditions like rhabdomyolysis-induced acute kidney injury.
No scientific awards are documented in the provided materials.
Dr. Allhorn has supervised 2 research works and participates in multiple funded projects. She is a key researcher in the RoxP project (investigating skin bacterium antioxidants), supported by the Crafoord Foundation, Swedish Society of Medicine, and 10+ Swedish foundations. She also contributes to SMIM1 protein research on metal ion homeostasis funded by Alfred Österlunds stiftelse, demonstrating strong national collaboration networks.
As an integral member of LUCC and StemTherapy initiatives, she operates within Lund University's collaborative infrastructure for cancer and regenerative medicine research. Her work leverages interdisciplinary teams to translate protein biochemistry discoveries into clinical applications for oxidative stress-related pathologies.
