معرفی
Marcus Ernst Peter, PhD, is the Tom D. Spies Professor of Cancer Metabolism and holds dual professorships in Medicine (Hematology/Oncology) and Biochemistry and Molecular Genetics at Northwestern University’s Feinberg School of Medicine. He leads the Peter Lab at the Robert H. Lurie Comprehensive Cancer Center, focusing on apoptosis, RNA interference, and novel cancer therapies. His work includes discovering the DISE mechanism (Death Induced by Survival Gene Elimination) and exploring CD95/CD95L signaling in cancer progression.
- Affiliations: Robert H. Lurie Comprehensive Cancer Center, Skin Biology and Diseases Resource-Based Center
- Editorial Roles: The EMBO Journal, Apoptosis, Oncogene
Research Interests: Cell Death Mechanisms (apoptosis, ferroptosis), RNAi-Based Therapies, Cancer Stem Cells, and MicroRNA Function. His team investigates how toxic RNAs trigger DISE to selectively kill cancer cells while sparing healthy tissue. Recent studies uncovered DISE’s role in Alzheimer’s neurodegeneration and aging.
Notable Achievements: Developed nanoparticle-delivered siRNA therapies targeting glioblastoma and ovarian cancer. Awards include the NCI Outstanding Investigator Award (2015) and Lefkofsky Scholar designation (2014).
Lab Team: Includes postdoctoral fellows (Monal Patel, Qadir Syed), graduate students (Ashley Haluck-Kangas, Tae-Eun Kim), and research scientists (Andrea Murmann). Contact: m-peter@northwestern.edu, 312-503-1291
