Marc Pelletier

Marc Pelletier, MD, MSc, serves as Division Chief of Cardiac Surgery at Yale School of Medicine and Physician-in-Chief of Cardiac Surgery for Yale New Haven Health System. He leads a multidisciplinary surgical team specializing in advanced cardiac interventions, with particular expertise in transcatheter aortic valve replacement (TAVR), minimally invasive valve surgery, aortic root reconstruction, and heart failure surgery. His clinical practice emphasizes team-based approaches integrating anesthesiology, perfusion technology, and AI-driven surgical innovations.

Dr. Pelletier holds an MD from Dalhousie University (1994) and completed prior academic appointments at Stanford University (Assistant Professor), Harvard Medical School (Surgical Director of TAVR), and Case Western Reserve University (Jay L. Ankeney Professor). He currently chairs the 2026 Society of Thoracic Surgeons Annual Meeting program committee.

His research focuses on improving cardiac surgical outcomes through innovations in minimally invasive techniques, hybrid revascularization, and postoperative recovery protocols. Recent work explores diaphragm pacing for ventilator weaning, biomarker applications in cardiac risk stratification, and advanced imaging for TAVR optimization. Publications demonstrate consistent focus on translating clinical data into improved patient management strategies.

• Leadership Roles: Program Chair, Society of Thoracic Surgeons 2026 Annual Meeting
• Endowed Professorship: Jay L. Ankeney Professorship in Cardiothoracic Surgery (Case Western Reserve University)

Dr. Pelletier leads Yale's cardiac surgery innovation initiatives, including robotic surgery programs and AI integration for surgical decision support. His team collaborates across cardiology, biomedical engineering, and outcomes research divisions to develop next-generation cardiac therapies.