معرفی
Manuela Tosin is an Associate Professor of Organic Chemistry at the University of Warwick, specializing in chemical biology and natural product biosynthesis. She leads the Organic Chemistry Teaching Section and is affiliated with the Royal Society of Chemistry (RSC) and American Chemical Society (ACS), particularly within the RSC Chemical Biology and Bioorganic Group.
- PhD in Chemistry (2004) from University College Dublin with Royal Irish Academy Prize
- Postdoctoral experience at University of Cambridge (Marie Curie Fellow) and University College Dublin
Her research focuses on developing chemical probes and tools to study:
- Mechanisms of natural product biosynthesis (polyketides, nonribosomal peptides)
- Engineering microbial factories for novel antibiotics/anticancer agents
- Glycosyltransferase enzyme function and biocatalysis applications
- Design of small-molecule inhibitors targeting disease-associated processes
Recent publications emphasize chemical probe applications for pathway analysis, VIP articles in Angewandte Chemie and ChemBioChem, and interdisciplinary approaches combining synthetic chemistry with structural biology and molecular biology.
Scientific awards include the Royal Irish Academy Prize for Young Chemists 2004. She supervises PhD students on topics spanning bacterial glycosyltransferases, chemo-enzymatic catalysis, and lipid biosynthesis in Rhodococcus.
