Manuel Penichet

Manuel Penichet is a Professor in the Department of Surgery and MIMG at the University of California Los Angeles (UCLA). His research focuses on cancer immunotherapy, antibody-based therapies, and molecular targeted treatment for malignancies such as multiple myeloma, AIDS-related lymphoma, and breast cancer. He is affiliated with UCLA’s David Geffen School of Medicine through his work in translational medicine.

Research Interests: Dr. Penichet develops monoclonal antibodies and fusion proteins targeting receptors like TfR1 and HER2/neu to induce tumor cell death via iron deprivation, immune stimulation, and apoptosis. His work also explores nanobioconjugates for brain tumor therapy and vaccine strategies for cancer prevention.

Article Trends: Recent publications highlight his contributions to preclinical models of HER2-positive cancers, combination therapies for multiple myeloma, and TfR1 inhibition in hematological and AIDS-related malignancies. Collaborations span immunology, oncology, and nanotechnology.

Scientific Awards:

• Suzanne Eaton, Ph.D. Memorial Prize
• Taylor M. Brown Memorial Award

Grants: Dr. Penichet has led NIH-funded projects (R01CA196266, R21CA193953, R01CA181115) investigating TfR1 targeting, immune disparities in myeloma, and anti-HER2/neu IgE therapy.