Manuel Maria Paz Castañal

Manuel Maria Paz Castañal is a Professor in the Department of Organic Chemistry at the University of Santiago de Compostela's Faculty of Chemistry. As a member of the COBINMA research group and affiliated with the Institute of Materials (iMATUS) and Strategic Grouping in Materials (AEMAT), he specializes in the synthesis of bioactive compounds, drug development, and molecular toxicology of anticancer agents like mitomycins.

• Education: PhD in Organic Chemistry (1994) from University of Santiago de Compostela
• Résumé: Thesis on asymmetric synthesis of biologically relevant compounds

Research Focus: His work combines organic synthesis with biomedical applications, particularly examining mitomycin C's DNA crosslinking mechanisms and creating nanoparticle-drug conjugates for enhanced cancer therapy. His studies span reaction mechanisms, stereochemical control, and drug-biomolecule interactions.

Publication Trends: Recent research highlights mitomycin-DNA adducts, nanoparticle drug delivery systems, and redox activation pathways, with significant contributions to understanding sequence selectivity and stereochemical configurations in DNA damage.

Collaborations: Active in interdisciplinary research networks, including Reactivity and Catalysis (ReactyCat) and pharmaceutical R&D (GI-1606) groups.