معرفی
Malcolm Whiteway is a Professor and Canada Research Chair in Microbial Genomics at Concordia University's Department of Biology. His research focuses on the genetics and genomics of the fungal pathogen Candida albicans, with emphasis on drug resistance mechanisms, antifungal therapies, and pathogenesis. He collaborates internationally on genomic projects and utilizes advanced techniques like transcriptomics and CRISPR-Cas9.
Education: PhD (University of Alberta).
Research Interests: Investigating Candida albicans metabolic pathways, regulatory circuits, and drug tolerance. Key projects include genome sequencing of yeasts, screening for antifungal synergies, and engineering yeast for industrial applications. His lab explores how transcription factors like Adr1 control ergosterol pathways and resistance to azoles.
Key Contributions: Identified novel antifungal targets, demonstrated FDA drugs' repurposing potential (e.g., pitavastatin), and mapped cellular responses to antifungals. His work bridges basic science and translational medicine.
Awards: Canada Research Chair in Microbial Genomics (2020–present).
Advising & Labs: Advises students on fungal genetics and drug discovery. His lab uses high-throughput screening and functional genomics to uncover therapeutic vulnerabilities in pathogens.
Lab Resources: Visit lab website for ongoing projects and collaborations.
