معرفی
Professor Malcolm MacLeod is a Professor of Neurology and Translational Neuroscience at the University of Edinburgh, serving as Co-Director of the Edinburgh Neuroscience Centre for Clinical Brain Sciences. He leads the Edinburgh CAMARADES group, which focuses on improving research rigor through systematic reviews and meta-analyses of animal studies. His work addresses bias in preclinical research and guides human clinical trial design.
- Academic Lead for Research Improvement and Research Integrity at the University of Edinburgh
- Member of the UK Reproducibility Network Steering Committee
- Convenor of EQIPD (www.eqipd.org)
His research integrates systematic reviews of animal models to inform clinical trials like EuroHYP-1 (brain cooling in stroke) and MS-SMART (secondary progressive multiple sclerosis). Key interests include reducing research waste, optimizing resource allocation, and understanding pathophysiological pathways in neurological diseases.
Collaborators include Prof David Howells (Melbourne), Prof Andrew Rice (Imperial College), and Prof Uli Dirnagl (Charite, Berlin). Funding sources include Horizon Europe, Wellcome Trust, and NC3Rs.
His team is involved in trials such as FOCUS (antidepressants post-stroke) and phase 1 brain cooling studies. Research groups include Prof Emily Sena, Dr Gillian Currie, and Dr Kaitlyn Hair.
