MARCOS RIOS GARCIA

Marcos Ríos García is a Ramón y Cajal researcher at the University of Santiago de Compostela, affiliated with the Department of Physiology and the Center for Research in Molecular Medicine and Chronic Diseases (CIMUS). His research focuses on molecular mechanisms linking metabolism and cancer, particularly the role of AMP-activated protein kinase (AMPK) in tumorigenesis and metabolic disorders. He holds a PhD from the University of Santiago de Compostela (2012), where his thesis investigated 'Role of AMPK in the regulation of metabolism and cell proliferation during tumorigenesis.'

His work integrates cancer biology, metabolic pathways, and molecular medicine, with recent contributions addressing DNA repair mechanisms, lipogenic responses in liver cancer, and obesity-related metabolic complications. Key projects include exploring small extracellular vesicle-mediated targeting of AMPKα1 to combat obesity and uncovering roles of HAND2 in adipogenesis. He collaborates with the MetaMol group on molecular metabolism studies.

Publications highlight interdisciplinary approaches, blending oncology with metabolic research (e.g., USP37/TRAIIP interactions in DNA replication stress, DIAPH1 deficiency in cancer, and BMP8B resistance in obesity). His findings contribute to therapeutic strategies targeting metabolic vulnerabilities in cancer and metabolic diseases.