معرفی
Lydia Grmai is an Associate Research Scientist in the Department of Comparative Medicine at Yale University's School of Medicine. Her research focuses on adipose tissue metabolism, Drosophila genetics, endocrinology, fertility mechanisms, and the interplay between aging and metabolic disorders. She holds a PhD in Biochemistry & Molecular Pharmacology from New York University School of Medicine (2017) and a BS in Biochemistry & Molecular Biology from the University of Maryland, Baltimore County (2011). Dr. Grmai's work combines molecular genetics, transcriptomics, and proteomics to study developmental processes and cellular signaling pathways in model organisms.
Her research interests include understanding how metabolic signals in fat tissues regulate reproductive processes such as oocyte maturation and ovulation. She also investigates sex determination mechanisms in Drosophila, particularly the role of genes like Sex lethal and Chinmo in germline differentiation. Her studies on stem cell niches and Activin signaling pathways contribute to broader insights into tissue homeostasis and cellular quiescence.
Dr. Grmai’s laboratory (Grmai Lab) employs Drosophila as a model system to explore fundamental biological questions with translational implications for human health. Key themes include metabolic regulation of reproduction, molecular mechanisms of sex identity maintenance, and the role of JAK-STAT signaling in cell competition and growth control. Her multidisciplinary approach integrates genomic, proteomic, and genetic tools to dissect complex biological systems.
