Luis Queme Cobar

Luis Queme Cobar serves as an Assistant Professor in the Department of Biomedical Sciences at the University of New England College of Osteopathic Medicine. His research program investigates neuro-immune interactions in chronic pain development following stress exposure, utilizing multidisciplinary approaches spanning molecular biology to AI-driven behavioral analysis.

Education:

• B.S. and M.D. from Francisco Marroquin University, Guatemala City (2007)
• Ph.D. in Cell Information Medicine from Nagoya University, Japan (2013)

Dr. Queme Cobar's research centers on peripheral sensory neuron interactions with non-neuronal cells (particularly macrophages) in chronic pain pathogenesis. His NIH-funded work employs ex-vivo electrophysiology, molecular techniques, and computational behavioral analysis to dissect mechanisms of muscle pain persistence. Key themes include sex-specific pain pathways, cardiovascular-pain reflex integration, and stress-induced neuroplasticity.

Publication analysis reveals consistent focus on muscle afferent physiology, with recent work emphasizing macrophage roles in pain chronification and AI-enhanced behavioral phenotyping. His research bridges basic neurobiology and translational pain medicine, particularly regarding ischemic myalgia and exercise-induced sensitization.

Scientific Awards:

• American Heart Association Postdoctoral Fellowship

Current NIH funding supports investigations into macrophage-mediated long-lasting muscle pain. Dr. Queme Cobar maintains active collaborations with Cincinnati Children's Hospital researchers from his postdoctoral training, where he studied muscle afferent dual roles in nociception and cardiovascular reflexes under Dr. Michael Jankowski's mentorship.

His laboratory integrates electrophysiology rigs, molecular biology suites, and machine learning pipelines for behavioral analysis, operating within the Graduate School of Biomedical Science and Engineering infrastructure at UNE.