معرفی
Louise Larose is an Associate Professor at the Department of Medicine, Faculty of Medicine and Health Sciences at McGill University, and holds an Honorary Investigator appointment at the Research Institute of the McGill University Health Centre (RI-MUHC), Glen site since 2021. Her work bridges molecular biology, diabetes research, and obesity mechanisms.
- Key Affiliations
- McGill University
- RI-MUHC
Research Focus:
Dr. Larose's research centers on:
- Intracellular signaling in metabolic disorders
- Adaptor protein biology (notably Nck family)
- Pancreatic β cell failure in diabetes
- Adipose tissue behavior in obesity
Her laboratory’s work on Nck adapter proteins represents the world's largest single-laboratory contribution to this field, revealing critical pathways like PDGFRα activation in adipogenesis and PERK pathway regulation in β cell homeostasis.
Publications Trends:
Over 15 years, her research explores:
- Molecular mechanisms of metabolic regulation
- Protein interaction networks in diabetes
- Translational implications for obesity therapies
- Cell signaling crosstalk in metabolic tissues
Academic Contributions:
Dr. Larose has mentored numerous students in McGill’s Experimental Medicine Program and led significant discoveries in:
- Nck1-IRE1α signaling axis
- PTP1B expression regulation
- Muscle differentiation via USP19
- Stress granule formation in aging
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