Andrey Cybulsky

Andrey V. Cybulsky is a Senior Scientist at the Research Institute of the McGill University Health Centre (RI-MUHC) and a Professor in the Department of Medicine at McGill University. His research focuses on understanding the molecular mechanisms of glomerular diseases, particularly those involving podocyte injury and immune-mediated processes.

Key research areas include:

• Pathophysiology of glomerulonephritis
• Role of phospholipases and protein kinases in renal injury
• Endoplasmic reticulum stress and proteostasis in podocytes
• Therapeutic targeting of SLK (Ste20-like kinase) and IRE1α pathways

Recent work highlights:

• Genetic models of phospholipase A2γ deletion in diabetic nephropathy
• Mechanistic studies on IRE1α-mediated ER-phagy
• Development of urinary biomarkers for ER stress
• SLK regulation of cytoskeletal dynamics in podocytes

His publications span high-impact nephrology and molecular biology journals, with a focus on translational approaches to chronic kidney disease.