معرفی
Lorenzo Angelo Cingolani is an Associate Professor of Physiology at the University of Trieste's Department of Life Sciences. He is a member of the Department Council, Course of Study Recommendations, Doctoral Colleges, and leads the Synaptic Neurophysiology research group.
His research focuses on synaptic physiology, neuroscience, and calcium channel regulation, with a particular interest in molecular mechanisms underlying brain connectivity. He investigates how cell adhesion molecules and alternative splicing of calcium channels contribute to synaptic specificity and diversity, aiming to develop therapies for disorders like autism, epilepsy, and ataxia. His work integrates optogenetics, genome editing, and magnetogenetics to repair neural circuits.
His selected articles highlight trends in synaptic plasticity, calcium channel diversity, and genetic interventions for neurological disorders. Key subfields include neurotransmission, receptor dynamics, neurodevelopment, and biomechanical properties of synapses.
Scientific Awards and Grants:
- European Research Council (SynMech; Horizon-EIC-2022-Pathfinderopen-01-01; ID: 101099579)
- Fondazione Cariplo (DIGAP; ID: 2019-3438)
- Ministero della Salute (DRACULA; Ricerca Finalizzata; ID: GR-2021-12375009)
- Fondazione Telethon (GGP19181)
- Collaborative funding with Fondazioni Telethon and Cariplo (GJC22053)
He mentors PhD students and postdocs in projects like SynMech, a European collaboration involving institutions in Germany, Netherlands, and Italy. His lab at the University of Trieste develops synaptic magnetogenetics for noninvasive treatment of drug-resistant brain disorders.