Lisa Frankel

Lisa Frankel is an Associate Professor at the Biotech Research & Innovation Centre (BRIC) within the Faculty of Health and Medical Sciences at the University of Copenhagen. Her research is centered at the intersection of RNA biology and cellular stress mechanisms, specifically focusing on the role of microRNAs in cancer pathogenesis and autophagy regulation. She maintains an active laboratory investigating the molecular mechanisms linking RNA processing with cellular degradation pathways.

Her educational background includes a B.Sc. in Biology (2004) and M.Sc. in Human Biology (2006), both from the University of Copenhagen. Her career trajectory shows continuous progression from Master Student (2005-2006) to Ph.D. Student (2006-) at BRIC, with research experience at the Danish Cancer Society.

Dr. Frankel's research program primarily investigates microRNA regulation in cancer, with particular emphasis on identifying novel microRNA targets and understanding microRNA biogenesis. Her recent work has expanded into the intersection of RNA biology and autophagy, examining how ribosomal homeostasis is maintained during cellular stress responses and oncogene-induced senescence. Her laboratory employs cutting-edge molecular and cellular techniques to dissect these complex regulatory networks.

Analysis of her recent publications reveals a strong research trajectory focused on the molecular mechanisms connecting RNA regulation with autophagy pathways in cancer contexts. Her work demonstrates increasing sophistication in connecting fundamental cellular processes like ribosome homeostasis with disease mechanisms, particularly in cancer biology. The progression from microRNA studies to more complex systems involving ribotoxic stress responses and autophagy regulation shows a maturing research program with significant translational potential.

Dr. Frankel maintains active collaborations across multiple institutions, as evidenced by her co-authorship on papers with researchers from various international laboratories. Her work has garnered attention across multiple platforms, with significant readership on academic networks like Mendeley and engagement on social media platforms including X (formerly Twitter) and Bluesky.

Her laboratory, situated within the Cell Stress and Survival research group at BRIC, focuses on the RNA and Autophagy unit, investigating fundamental cellular processes with implications for cancer therapeutics. The research environment at BRIC provides state-of-the-art facilities for molecular and cellular investigations into these critical biological pathways.