معرفی
Dr. Lesley Greene is an Associate Professor and Associate Dean in the Department of Chemistry & Biochemistry at Old Dominion University (ODU). She holds a Ph.D. in Biochemistry from the University of Miami (1998) and a B.S. in Microbiology from the same institution (1991). Her post-doctoral research was conducted at the University of Oxford and University College London.
Her research integrates computational and experimental approaches to study:
- Protein folding mechanisms and misfolding pathologies
- Evolution of protein structures and complexes
- Bioinformatic analysis of protein networks
- Genetic adaptation in changing environments
- Biophysical characterization using NMR, CD spectroscopy, and stopped-flow techniques
Her publications demonstrate a consistent focus on protein dynamics, with recurring themes in NMR spectroscopy, evolutionary conservation of structural motifs, and computational modeling of folding pathways. Recent work explores amyloid formation mechanisms and environmental adaptation in microorganisms.
Awards & Honors:
- John R. Broderick Diversity Champion Award (2017)
- Most Inspiring Faculty Mentor (2009, 2010)
Research Funding: Principal Investigator on multiple grants including NSF-supported projects on protein structure networks ($200,000), Jeffress Trust Awards ($20,000-$22,000), and SEECR grants for bioinformatics education tools. Manages shared laboratory facilities with protein purification systems, NMR spectrometers, and computational clusters.
Student Advising: Currently mentors PhD candidates John Bedford (protein topology), Zeinab Haratipour (interaction networks), and Cherrelle Barnes (cyanobacteria engineering). Alumni include 5 PhD graduates in biochemistry and computational biology.
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