Lea Sayce

Lea Sayce is a Research Assistant Professor at the University of Pittsburgh's Department of Communication Science and Disorders. Her research focuses on the molecular, cellular, and biomechanical aspects of voice disorders, with particular emphasis on treatment optimization and the pathobiology of vocal fold injuries. Sayce holds a PhD in Biochemistry from the University of Oxford and a BS in Biochemistry (Neuroscience) from the University of Surrey. She has transitioned between industry roles and clinical research, currently emphasizing translational studies in voice disorder interventions.

Education:

• Doctor of Philosophy in Biochemistry, University of Oxford
• Bachelor of Science in Biochemistry (Neuroscience), University of Surrey

Research Interests: Sayce's work spans molecular mechanisms of voice disorders, biomechanical modeling of vocal fold vibration, and clinical optimization of surgical interventions like thyroplasty. Her computational tools (e.g., PhonoSim) aim to enhance pre-surgical planning through subject-specific simulations. Recent projects explore steroid effects on vocal fold healing and the biomechanical impact of vocal fold paralysis.

Publications Trends: Her 2023–2025 work highlights advancements in computational modeling of vocal fold dynamics, preclinical testing of surgical implants, and pharmacological interventions for vocal injuries. A 2020 paper emphasizes genetic approaches for voice disorder diagnosis, reflecting her interdisciplinary approach.

Advising & Grants: While no specific grants are mentioned, her publications suggest ongoing collaborations across bioengineering and clinical otolaryngology. She advises on vocal fold injury mechanisms and surgical innovation.