معرفی
Kyle Gregory is a Researcher in the Department of Life Sciences at the University of Bath. His work focuses on structural biology, enzymology, and neurotoxin research, contributing to UN Sustainable Development Goals through advancements in drug design and protein mechanisms. Key areas include angiotensin-converting enzyme (ACE) inhibitors, bacterial neurotoxins, and covalent protein linkages.
Research highlights include elucidating the molecular basis of ACE inhibition by ciprofloxacin and diprolyl-derived compounds, structural studies of Drosophila ACE homologues, and exploring novel covalent bonds in proteins. His findings bridge biochemistry and pharmacology, with implications for antibiotic mechanisms and hypertension treatments.
Gregory completed his PhD in 2023 on Clostridium botulinum neurotoxin structural analysis, advised by Prof. Acharya. His thesis, 'Structural analysis of Clostridium botulinum neurotoxins (BoNTs)', received notable attention across 6 news outlets and 4 Mendeley readers. Collaborative work spans international teams, with recent outputs in ACS Bio & Med Chem Au, Biomolecules, and Chemical Communications.
