Kristy R. Stengel

Kristy R. Stengel is an Assistant Professor in the Department of Cell Biology at Albert Einstein College of Medicine, holding the Melissa S. and John V. Ceriale Early Career Professorship. Her research focuses on understanding how sequence-specific transcription factors regulate cellular adaptation and disease progression, particularly in cancer and developmental disorders. Her work employs chemical-genetic approaches to degrade endogenous transcription factors rapidly, enabling real-time analysis of transcriptional networks and chromatin dynamics.

Research interests include the interplay between transcription factors and chromatin structure, enhancer-promoter communication, and mechanisms of tumor development. Key techniques involve genome-wide analysis of transcription factor occupancy, nucleosome positioning studies, and functional genomics assays.

Publications highlight investigations into SMARCA5’s role in nucleosome spacing, PAX3-FOXO1’s regulation of enhancer architecture in sarcoma, and AML1-ETO’s oncogenic transcriptional circuits in leukemia. Collaborative efforts with experts in epigenetics and cancer biology underscore her interdisciplinary approach.

Advising and grants sections remain unspecified in available data. No lab or team affiliations are explicitly mentioned.